- 簡(jiǎn)介
- 科研領(lǐng)域
- 學(xué)術(shù)發(fā)表
個(gè)人簡(jiǎn)介
2007年5月 香港中文大學(xué) 學(xué)士
2009年5月 香港中文大學(xué) 碩士
2017年5月 杜克大學(xué) 博士
2017年11月-2022年4月 加州大學(xué)洛杉磯分校 博士后
2022年7月至今 北京大學(xué)現(xiàn)代農(nóng)業(yè)研究院
教育經(jīng)歷
工作經(jīng)歷
科研領(lǐng)域
全球氣候變化以及大規(guī)模的單一種植，使得作物更頻繁的受到溫度和疾病的脅迫。溫度脅迫影響植物生長發(fā)育的每個(gè)階段，造成嚴(yán)重減產(chǎn)；且高溫高濕環(huán)境更容易導(dǎo)致病毒病的大規(guī)模爆發(fā)。目前對(duì)于病毒病的爆發(fā)，我們尚無有效的治理措施。辣椒是我國經(jīng)濟(jì)價(jià)值最高的作物，其對(duì)于溫度和病毒極為敏感。本課題組針對(duì)辣椒應(yīng)對(duì)高低溫脅迫以及病毒病的抗性進(jìn)行研究。具體研究方向包括：
1. 品種資源收集和篩選對(duì)于高低溫和病毒病具有抗性的辣椒品種，并在此基礎(chǔ)上通過育種，對(duì)辣椒進(jìn)行品種改良。
2. 對(duì)具有抗性的辣椒品種進(jìn)行深入的分子機(jī)制研究。
學(xué)術(shù)發(fā)表
1. Wang, Q.,* Xue, Y.,* Zhang, L.,* Zhong, Z., Feng, S., Wang, C., Xiao, L., Yang, Z., Harris, CJ., Wu, Z., Zhai, J.,Yang, M., Li, S., Jacobsen, SE. and Du, J. (2021) Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation. Science, 374:1152-1157.
*Equal contribution
2. Xue, Y.*, Zhong Z.*, Harris CJ.*, Gallego-Bartolomé, J., Wang, M., Picard, C., Cao, X., Hua, S., Kwok, I., Feng, S., Jami-Alahmadi, Y., Sha, J., Gardiner, J., Wohlschlegel, J. and Jacobsen, SE. (2021) Arabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation. Nature Communications, 12:4292.
3. Jiang, Z., Zhou, X., Tao, M., Yuan, Y., Liu, L., Wu, F., Wu, X., Xiang, Y., Niu, Y., Liu, F., Li, C., Ye, R., Byeon, B., Xue, Y., Zhao, H., Wang, S., Crawford, B., Johnson, M., Hu, C., Pei, C., Zhou, W., Swift, G., Zhang, H., Vo-Dinh, T., Hu, Z., Siedow, J. and Pei, Z. (2019) Plant cell-surface GIPC sphingolipids sense salt to trigger Ca2+ influx. Nature, 572: 341-346.
4. Kim, HJ., Yen, L, Wongpalee, SP., Kirshner, JA., Mehta, N., Xue, Y., Johnston, JB., Burlingame, AL., Kim, JK., Loparo JJ., and Jacobsen, SE. (2019). The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction. Molecular Cell, 75: 700-71
5. Harris, CJ., Scheibe, M., Wongpalee, SP., Liu, W., Cornett, EM., Vaughan, RM., Li, X., Chen, W., Xue, Y., Zhong, Z., Yen, L., Barshop, WD., Rayatpisheh, S., Gallego-Bartolome, J., Groth, M., Wang, Z., Wohlschlegel, JA., Du, J., Rothbart, SB., Butter, F., and Jacobsen, SE. (2018). A DNA methylation reader complex that enhances gene transcription. Science, 6419: 1182-1186.
6. Yuan, F., Yang, H.*; Xue, Y.*; Kong, D., Ye, R., Li, C., Zhang, J., Theprungsirikul, L.,Shrift, T., Krichilsky, B., Johnson, DM., Swift, GB., He, Y., Siedow, JN. and Pei, ZM.(2014). OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing inArabidopsis. Nature. 514: 367-371*equal contribution
7. Jiang, Z., Zhu, S., Ye, R., Xue, Y., Chen, A., An, L. and Pei, ZM. (2013). Relationship between NaCl- and H2O2-Induced cytosolic Ca2+ Increases in response to stress in Arabidopsis. PloS one. 8: 10
8. Cheung, MY., Xue, Y., Zhou, L., Li, MW., Sun, SSM. and Lam, HM. (2010) An ancient Ploop GTPase in rice is regulated by a higher plant-specific regulatory protein. Journal of Biololgical Chemistry. 285:37359–37369.
9. Cheung, MY., Zeng, NY., Tong, SW., Li, FWY., Xue, Y., Zhao, KJ., Wang, C., Zhang, Q., Fu, Y., Sun, Z., Sun, SSM. and Lam, HM. (2008) Constitutive expression of a rice GTPase activating protein induces defense responses. New Phytologist. 179:530-545