- 簡介
- 科研領域
- 學術發(fā)表
個人簡介
2007-2014 中國農(nóng)業(yè)科學院，作物科學研究所，理學博士
2014-2019 美國加州大學洛杉磯分校，分子、細胞及發(fā)育生物學系，博士后
2019-2022 美國加州大學洛杉磯分校，分子、細胞及發(fā)育生物學系，助理項目科學家
2022-至今 北京大學現(xiàn)代農(nóng)業(yè)研究院，研究員
教育經(jīng)歷
工作經(jīng)歷
科研領域
光作為最重要的環(huán)境因子之一，不僅是植物生存的直接能量來源，也是調(diào)節(jié)植物生長發(fā)育的關鍵信號。植物通過體內(nèi)不同的光受體蛋白感知周圍環(huán)境光的變化，調(diào)節(jié)自身的生理代謝狀態(tài)和生長發(fā)育程序以適應環(huán)境。深入理解植物對環(huán)境光信號的響應機制，不僅具有重要的科學價值，同時也能為作物育種和品質(zhì)改良提供理論指導。本實驗室的研究方向之一是植物藍光受體和藍光信號轉(zhuǎn)導的分子機制。
辣椒是我國第一大蔬菜，其果實特有的天然產(chǎn)物辣椒素和辣椒紅素廣泛應用于食品、保健、醫(yī)藥衛(wèi)生和工業(yè)等眾多領域，市場需求巨大。但以提升這兩種物質(zhì)含量為目標的辣椒育種實踐嚴重受限于狹窄的種質(zhì)資源和滯后的基礎研究。本實驗室的另一研究方向是利用多組學聯(lián)合分析，結合遺傳學、細胞生物學、生物化學和分子生物學、以及結構生物學手段，系統(tǒng)解析辣椒紅素和辣椒素生物合成和代謝途徑的細胞學和分子遺傳調(diào)控機制，為培育提取工業(yè)用途的辣椒新品種提供理論基礎。
學術發(fā)表
1. Jiang, B., Zhong, Z., Gu, L., Zhang, X., Wei, J., Lin, G., Qu, G., Xiang, X., Wen, C., Gateas, M., Serres, J., Wang, Q., He, C., Wang, X.#, and Lin, C.# (2023). Photo-condensation of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis. Nature Plants. (https://doi.org/10.1038/s41477-023-01580-0.). (#共同通訊作者)
2. Jiang, B., Zhong, Z., Su, J., Zhu, T., Yueh, T., Bragasin, J., Bu, V., Zhou, C., Lin, C. and Wang, X.# (2023). Co-condensation with photoexcited Cryptochromes facilitates MAC3A to positively control hypocotyl growth in Arabidopsis. Science Advances. 9, eadh4048. (#)
3. Liu, S.*, Zhang, L.*, Hu, X., Chen, Y., Zhang, S., Zhao, Q., Bie, Y., Wang, X.# and Wang, Q.# (2022). Differential photoregulation of the nuclear and cytoplasmic CRY1 in Arabidopsis. New Phytologist.234: 1332-1346.(#)
4. Wang, X.*, Jiang, B.*, Gu, Lianfeng.*, Chen, Y., Mora, M., Zhu, M., Noory, E., Wang, Q.# and Lin, C.# (2021). A photoregulatory mechanism of the circadian clock in Arabidopsis. Nature Plants. 7: 1397.
5. Cheng, Z., Zhang, X., Huang, P., Huang, G., Zhu, J., Chen, F., Miao, Y., Liu, L., Fu, Y-F#. and Wang, X.#(2020). Nup96 and HOS1 are Mutually Stabilized and Gate CONSTANS Protein Level, Conferring Long-day Photoperiodic Flowering Regulation in Arabidopsis. Plant Cell. 32: 374 (#)
6. Wang, X., Wang, Q., Han, Y.-J., Liu, Q., Gu, L., Yang, Z., Su, J., Liu, B., Zuo, Z., He, W., Wang, J., Liu, B., Matsui, M., Kim, J.-I., Oka, Y. and Lin, C. (2017). A CRY-BIC negative-feedback circuitry regulating blue light sensitivity of Arabidopsis. Plant Journal, 92: 426.
7. Wang, Q*., Zuo Z.*, Wang, X.*, Gu, L., Yoshizumi, T., Yang, Z., Yang, L., Liu, Q., Liu W., Han, Y., Liu B., Wohlschlegel, J., Matsui, M., Oka, Y. and Lin, C. (2016). Photoactivation and inactivation of Arabidopsis cryptochrome 2. Science. 354: 343. (*)
8. Gao, J.*, Wang, X, Zhang, M., Bian, M., Deng, W., Zuo, Z., Yang, Z., Zhong, D., and Lin, C. (2015). Trp triad-dependent rapid photoreduction is not required for the function of Arabidopsis CRY1. PNAS, 112: 9135. (*)
9. Yang, L.*, Wang, X.*, Deng, W., Mo, W., Liu, Q., Zhang, C., Wang, Q., Lin, C and Zuo, Z. (2016). Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Frontiers in Plant Science, 7:940. (*)
10. Wang, X., Fan,C., Zhang,X., Zhu,J. and Fu, Y. (2013). BioVector, a flexible system for gene specific-expression in plants. BMC Plant Biology, 13:198.
11. Fan, C.*, Wang, X.*, Wang, Y., Hu, R., Zhang, X., Chen, J. and Fu, Y. (2013). Genome-Wide Expression Analysis of Soybean MADS Genes Showing Potential Function in the Seed Development. PLoS ONE, 8: e62288. (*)
12. Wang, Q.*, Liu, Q.*, Wang, X., Zuo Z., Oka, Y. and Lin, C. (2018). New insights into the mechanisms of phytochrome-cryptochrome coaction. New Phytologist, 217: 547.
13. Wang, Q., Zuo, Z., Wang, X., Liu, Q., Gu, L., Oka, Y. and Lin, C. (2018). Beyond the photocycle — how cryptochromes regulate photoresponses in plants. Current Opinion in Plant Biology, 45:120
14. Liu, L.*, Jiang, Y. *, Zhang, X. *, Wang, X., Wang, Y., Han, Y., Coupland, G., Jin, J., Searle, I., Fu Y. and Chen, F. (2017). Two SUMO Proteases SUMO PROTEASE RELATED TO FERTILITY1 and 2 Are Required for Fertility in Arabidopsis. Plant Physiology, 175:1703.
15. Liu, Q., Wang Q., Deng W.,Wang X., Piao M., Cai D., Li Y., Barshop W., Yu X., Zhou T., Liu B., Oka Y., Wohlschlegel J., Zuo Z. and Lin C. (2017). Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2. Nature Communications. 8: 15234.
16. Liu, Q., Wang, Q., Liu, B., Wang, W., Wang, X., Park, J., Yang, Z., Du, X., Bian, M. and Lin, C. (2016). The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases. Plant & Cell Physiology, 57: 2175
17. Li, Q., Fan, C., Zhang, X., Wang, X., Wu, F., Hu, R. and Fu, Y. (2014). Identification of a Soybean MOTHER OF FT AND TFL1 Homolog Involved in Regulation of Seed Germination. PLoS ONE, 9: e99642.
18. Fan, C., Hu, R., Zhang, X., Wang, X., Zhang, W., Zhang, Q., Ma, J. and Fu, Y. (2014) Conserved CO-FT regulons contribute to the photoperiod flowering control in soybean. BMC Plant Biology. 14:9.
19. Fan, C., Wang, X., Hu, R., Wang, Y., Xiao, C., Jiang, Y., Zhang, X., Zheng, C. and Fu, Y. (2013) The pattern of Phosphate transporter 1 genes evolutionary divergence in Glycine max L. BMC Plant Biology.13:48.
20. Wang, X.#, Liu, Q., He, W., Lin, C. and Wang, Q#. (2019). Characterization of Flowering Time Mutants. In: Hiltbrunner A. (eds) Phytochromes. Methods in Molecular Biology, vol 2026. Humana, New York, NY. (#)
21. Wang, X. # Wang, Q., Nguyen, P. and Lin, C. (2014). Cryptochrome-mediated light responses in plants. Enzymes. 35:167-89. ( #)